Retinoic Acid Receptor beta anticorps (N-Term)

N° du produit ABIN361388

L’anticorps Souris Monoclonal anti-Retinoic Acid Receptor beta a été validé pour WB. Il convient pour détecter Retinoic Acid Receptor beta dans des échantillons de Humain.

Aperçu rapide pour Retinoic Acid Receptor beta anticorps (N-Term) (ABIN361388)

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoic Acid Receptor beta est non-conjugé

Application: Western Blotting (WB)

Clone: 336

Détail du produit anti-Retinoic Acid Receptor beta anticorps

Épitope: N-Term

Specificité: Specific for the ~48k RAR-( isotype.

Réactivité croisée: Humain, Rat (Rattus)

Homologie: canine, guinea pig, mouse, non-human primate

Purification: Protein G purified culture supernatant

Immunogène: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Isotype: IgG1

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur Retinoic Acid Receptor beta

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Autre désignation: RARB

Sujet: Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRa, ß and () preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti- Retinoic Acid Receptor, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RAR-ß isotype.

Poids moléculaire: '48 kDa

ID gène: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway